Foveolar Choroidal Circulation and Choroidal Neovascularization in Age-Related Macular Degeneration

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Foveolar choroidal circulation and choroidal neovascularization in age-related macular degeneration.

PURPOSE To investigate in a longitudinal study whether foveolar choroidal blood flow changes are associated with the development of choroidal neovascularization (CNV) in AMD. METHODS Relative foveolar choroidal blood velocity (ChBVel), volume (ChBVol), and flow (ChBFlow) were assessed in 135 patients with AMD, at baseline and then annually with laser Doppler flowmetry. All study eyes had visu...

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Transpupilary thermotherapy of occult subfoveal choroidal neovascularization secondary to age related macular degeneration

 Abstract Background: Transpupillary thermotherapy is a new treatment for subfoveal choroidal neovascularization which needs further evaluation. This study was aimed to evaluate the efficacy of transpupillary thermotherapy on regression of occult subfoveal choroidal neovascularization with or without pigment epithelial detachment in patients with age-related macular degeneration. Methods: In a ...

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Choroidal neovascularization and age-related macular degeneration.

and dysfunctional RPE are thought to be pivotal.66 CSR is a common maculopathy that can adversely affect central visual function and is 6-fold more common in males than females.67 Affected patients are typically between 30 and 50 years of age. Many putative risk factors exist for the development of CSR, the most conclusive being any form of exogenous corticosteroid use. Other risk factors inclu...

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Foveolar choroidal blood flow in age-related macular degeneration.

PURPOSE To compare measurements of the foveolar choroidal blood circulation in subjects with nonexudative, age-related macular degeneration (AMD) with those of control subjects. METHODS Laser Doppler flowmetry was used to assess relative choroidal blood velocity (ChBVel), volume (ChBVol), and flow (ChBFlow) in the center of the fovea. Measurements were obtained in 20 eyes of 20 subjects with ...

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Measurement of Choroidal Neovascular Area in Age-Related Macular Degeneration using Modified Otsu’s Thresholding Method

Introduction: Age-related Macular Degeneration (AMD) is one of the most important causes of irreversible  blindness in the developed world and  prevents the affected  person from  performing simple tasks such  as  reading,  driving  and  facial  recognition.  In  the  AMD,  new  blood  vessels  grow  underneath  the  retina  in  a  process  called  choroidal  neovascularisation  (CNV).  There  ...

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ژورنال

عنوان ژورنال: Investigative Opthalmology & Visual Science

سال: 2008

ISSN: 1552-5783

DOI: 10.1167/iovs.07-0526